Spurs vs. 76ers Predictions, Odds & Stats – March 21

Philadelphia 76ers v Portland Trail Blazers

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The San Antonio Spurs (29-39) are favored by 5.5 points against the Philadelphia 76ers (23-46) on Friday, March 21, 2025 at 8 p.m. ET. The matchup airs on FDSSW and NBCS-PH.

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Spurs vs. 76ers Predictions for Friday

Our computer model for this encounter calls for a final tally of Spurs 117, 76ers 111.

  • Moneyline Pick: Spurs (-240)
  • Total Pick: Under 235.5 (computer predicts 227.9 points)
  • Pick ATS: 76ers (+5.5)

Recent Spurs vs. 76ers Matchups

Spurs vs 76ers (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
12/23/2024 76ers -5.5 217.5 -205 +171 111-106 PHI
4/7/2024 76ers -4.5 225.5 -186 +154 133-126 PHI
1/22/2024 76ers -13.5 237 -1040 +667 133-123 PHI

Spurs 2024-25 Betting Trends

  • San Antonio is 30-38-0 against the spread this season.
  • In games this season they were favored by 5.5 points or more, the Spurs have a 3-6 record against the spread.
  • San Antonio has gone over in 38 of its 69 games with a set total (55.1%).
  • This season, the Spurs have won 15 out of the 22 games, or 68.2%, in which they've been favored.
  • San Antonio has a record of 5-3 when it's favored by -240 or more by oddsmakers this season.

76ers 2024-25 Betting Trends

  • Philadelphia is 26-43-0 against the spread this season.
  • When they have played as at least 5.5-point underdogs this year, the 76ers are 16-12 against the spread.
  • The teams have combined to hit the over in 41 of Philadelphia's 69 games with a set total.
  • The 76ers have been the underdog on the moneyline 42 total times this season. They've finished 10-32 in those games.
  • When playing as a moneyline underdog with odds of +196 or longer, Philadelphia has a record of 6-19 (24%).

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Spurs vs. 76ers Injury Report

Spurs

Spurs:

Charles Bassey: Out (Knee),

De'Aaron Fox: Out For Season (Hand),

Victor Wembanyama: Out For Season (Illness)

76ers

76ers:

Joel Embiid: Out For Season (Knee),

Adem Bona: Out (Ankle),

Kelly Oubre Jr.: Out (Knee),

Tyrese Maxey: Out (Back),

Lonnie Walker IV: Probable (Head),

Andre Drummond: Out (Toe),

Kyle Lowry: Out (Hip),

Jared McCain: Out For Season (Meniscus),

Paul George: Out For Season (Groin),

Eric Gordon: Out For Season (Wrist)

Spurs vs. 76ers Game Time and TV Channel

  • Game day: Friday, March 21, 2025
  • Game time: 8 p.m. ET
  • TV channel: FDSSW and NBCS-PH
  • Location: San Antonio, Texas
  • Arena: Frost Bank Center
  • Live stream: Watch this game on Fubo (Regional restrictions may apply)

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