Texas Tech vs. Houston Football Prediction & Odds - Oct. 4

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The No. 11 Texas Tech Red Raiders (4-0) and the Houston Cougars (4-0) square off on Saturday, October 4, 2025 at TDECU Stadium in a clash of Big 12 opponents.

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Texas Tech vs. Houston Matchup Info

  • Game date: Saturday, October 4, 2025
  • Game time: 7 p.m. ET
  • Location: Houston, Texas
  • Venue: TDECU Stadium
  • TV channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Texas Tech vs. Houston Odds and Prediction

  • Spread favorite: Red Raiders (-13.5)
  • Moneyline: Red Raiders (-529), Cougars (+394)
  • Total: 51.5 points
  • Pick ATS: Houston (+13.5)
  • Pick OU: Over (51.5)
  • Prediction: Texas Tech 34, Houston 21

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Texas Tech vs. Houston Betting Records and Insights

  • Texas Tech has covered four times in four games with a spread this season.
  • Houston has put together a 3-1-0 record against the spread this year.
  • When playing as at least 13.5-point favorites this season, the Red Raiders have an ATS record of 3-0.
  • So far this season, two Texas Tech games have hit the over.
  • Houston games have hit the over three out of four times this year.

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