Houston vs. Oklahoma St Football Prediction & Odds - Oct. 11

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The Houston Cougars (4-1) take on a conference opponent when they visit the Oklahoma State Cowboys (1-4) on Saturday, October 11, 2025 at Boone Pickens Stadium in a Big 12 battle.

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Houston vs. Oklahoma State Matchup Info

  • Game date: Saturday, October 11, 2025
  • Game time: 12 p.m. ET
  • Location: Stillwater, Oklahoma
  • Venue: Boone Pickens Stadium
  • TV channel: TNT

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Houston vs. Oklahoma State Odds and Prediction

  • Spread favorite: Cougars (-14.5)
  • Moneyline: Cougars (-613), Cowboys (+441)
  • Total: 48.5 points
  • Pick ATS: Houston (-14.5)
  • Pick OU: Over (48.5)
  • Prediction: Houston 38, Oklahoma State 15

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Houston vs. Oklahoma State Betting Records and Insights

  • Houston has compiled a 3-2-0 ATS record so far this year.
  • Oklahoma State has a record of just 1-4-0 against the spread this year.
  • The Cougars have been favored by 14.5 points or more once this season, and covered the spread.
  • The Cowboys have been an underdog by 14.5 points or more three times this season, and covered the spread in one of those games.
  • So far this season, three of Houston's five games have hit the over.
  • So far this year, two Oklahoma State games have hit the over.

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