TCU vs. Iowa St Football Prediction & Odds - Nov. 8

TCU v West Virginia

Photo: Brien Aho / Getty Images Sport / Getty Images

Big 12 opponents match up when the TCU Horned Frogs (6-2) and the Iowa State Cyclones (5-4) play on Saturday, November 8, 2025 at Amon G. Carter Stadium.

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TCU vs. Iowa State Matchup Info

  • Game date: Saturday, November 8, 2025
  • Game time: 3:30 p.m. ET
  • Location: Fort Worth, Texas
  • Venue: Amon G. Carter Stadium
  • TV channel: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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TCU vs. Iowa State Odds and Prediction

  • Spread favorite: Horned Frogs (-7)
  • Moneyline: Horned Frogs (-270), Cyclones (+217)
  • Total: 57.5 points
  • Pick ATS: Iowa State (+7)
  • Pick OU: Under (57.5)
  • Prediction: TCU 29, Iowa State 25

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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TCU vs. Iowa State Betting Records and Insights

  • TCU has put together a 4-3-1 record against the spread this season.
  • Iowa State is 3-5-1 ATS this season.
  • The Horned Frogs have covered the spread once this season (1-2 ATS) when playing as at least 7-point favorites.
  • TCU and its opponent have combined to hit the over four out of eight times this season.
  • Iowa State games have hit the over four out of nine times this year.

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